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Omtrent seven-9 % af den kaukasiske befolkning har variationer i CYP2D6 genet som koder for ingen- eller nedsat aktivitet af CYP2D6 (se personlig medicin ). Tramadol et produg der omdannes til den aktive metabolit by way of CYP2D6. Patienter med nedsat eller manglende aktivitet af CYP2D6, vil have reduceret- eller manglende effekt af tramadol.Patie
The Federal Minister for Overall health Karl Lauterbach (SPD) presented the main concrete Thoughts for its implementation inside the autumn of 2022, inside of a document on The main element details, in what constituted a draft regulation that must have been Prepared by the end of March 2023.In the next step from the 2024 cannabis legalisation, prof